Selected Antimicrobial Information – Farm Animal
Amoxicillin-Clavulanic Acid [Farm Animal]
Restriction Status
Unrestricted
Dose
Species | Usage | Dose |
---|---|---|
Camelids | Label dose | No labeled dose. |
Cattle | Label dose | No labeled dose. |
Small Ruminants | Label dose | No labeled dose. |
Swine | Label dose | No labeled dose. |
Brand Name(s)
Clavamox®
Background
Amoxicillin-clavulanic acid is a bactericidal, time-dependent β-lactam antibiotic with improved activity against Gram-negative organisms when compared to penicillin. The addition of clavulanic-acid improves activity against β-lactamase-producing bacteria. Activity against Gram-positive organisms is comparable to amoxicillin and ampicillin. Amoxicillin-clavulanic acid distributes widely through the plasma, and can cross the blood-brain barrier when meninges are inflamed although it is uncertain if therapeutic concentrations are achieved. It does not penetrate abscesses or sites of tissue necrosis well. Excretion is primarily as unchanged drug in urine.
Current Uses within OSU-VMC
- Susceptible pathogens
Contraindicated Uses
- May not be practical to use in large animals due to cost.
Illegal Uses
- None
Formulations Available within the OSU Pharmacy
- Clavamox 62.5mg/ml oral suspension (15 ml bottle)
- Clavamox 62.5mg tablet
- Clavamox 125mg tablet
- Clavamox 250mg tablet
- Clavamox 375mg tablet
Notes
- None.