Selected Antimicrobial Information – Companion Animal
Cefazolin [Companion]
Restriction Status
Unrestricted
Dose
| Species | Usage | Dose |
|---|---|---|
| Cats | For surgical prophylaxis | 20-22mg/kg IV once 60min prior to incision, repeated q90-120min until wound closure (extra-label use) |
| For susceptible infections |
15-35mg/kg IV, IM, or SQ q6-8h (extra-label use) | |
| Dogs | For surgical prophylaxis | 20-22mg/kg IV once 60min prior to incision, repeated q90-120min until wound closure (extra-label use) |
| For susceptible infections | 15-35mg/kg IV, IM, or SQ q6-8h (extra-label use) |
Brand Name(s)
Ancef®, Kefzol®, Zolicef®
Background
Cefazolin is a bactericidal, time-dependent first generation cephalosporin (β-lactam) antibiotic with activity primarily against Gram-positive aerobes, and more limited activity against Gram-negative aerobes. Activity is poor against anaerobes. Cefazolin is not effective against Enterococcus spp., Pseudomonas aeruginosa, and methicillin-resistant Staphylococcus
Acceptable Uses
- Surgical prophylaxis, particularly for prolonged orthopedic procedures. Most efficacious against Gram-positive aerobic organisms. Poor choice for colorectal surgery.
- Treatment for systemic infections (e.g. sepsis) caused by susceptible organisms.
Unacceptable Uses
- N/A
Formulations Available within the OSU Pharmacy
- Cefazolin 1g/10ml injectable suspension
Notes
- N/A
