Selected Antimicrobial Information – Farm Animal

Amoxicillin-Clavulanic Acid [Farm Animal]

Restriction Status

Unrestricted

Dose

Species Usage Dose
Camelids Label dose No labeled dose.
Cattle Label dose No labeled dose.
Small Ruminants Label dose No labeled dose.
Swine Label dose No labeled dose.

Brand Name(s)

Clavamox®

Background

Amoxicillin-clavulanic acid is a bactericidal, time-dependent ╬▓-lactam antibiotic with improved activity against Gram-negative organisms when compared to penicillin. The addition of clavulanic-acid improves activity against ╬▓-lactamase-producing bacteria. Activity against Gram-positive organisms is comparable to amoxicillin and ampicillin. Amoxicillin-clavulanic acid distributes widely through the plasma, and can cross the blood-brain barrier when meninges are inflamed although it is uncertain if therapeutic concentrations are achieved. It does not penetrate abscesses or sites of tissue necrosis well. Excretion is primarily as unchanged drug in urine.

Current Uses within OSU-VMC

  • Susceptible pathogens

Contraindicated Uses

  • May not be practical to use in large animals due to cost.

Illegal Uses

  • None

Formulations Available within the OSU Pharmacy

  • Clavamox 62.5mg/ml oral suspension (15 ml bottle)
  • Clavamox 62.5mg tablet
  • Clavamox 125mg tablet
  • Clavamox 250mg tablet
  • Clavamox 375mg tablet

Notes

  • None.

License

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OSU VMC Antimicrobial Use Guidelines Copyright © 2018 by The Ohio State University College of Veterinary Medicine is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.