Selected Antimicrobial Information – Farm Animal
Florfenicol [Farm Animal]
Restriction Status
Unrestricted
Dose
| Species | Usage | Dose |
|---|---|---|
| Camelids | For respiratory disease, interdigital necrobacillosis (foot rot), or pododermatitis | 20mg/kg IM or SQ q24h (extra-label use) |
| Cattle | Nuflor® Label dose | 20mg/kg IM q48h or 40mg/kg SQ once; do not give more than 10mL per injection site |
| Nuflor Gold® Label dose | 40mg/kg SQ once; do not give more than 15mL per injection site | |
| Small Ruminants | For respiratory disease, interdigital necrobacillosis (foot rot), or pododermatitis | 20mg/kg IM q24h for 2d (extra-label use) |
| Swine | Label dose | No labeled dose. |
Brand Name(s)
NuFlor®, Nuflor Gold®, Resflor Gold®
Background
Florfenicol is a time-dependent, bacteriostatic acetamide antibiotic with a very broad spectrum of activity, including Gram-positive and Gram-negative aerobes, and anaerobes. Florfenicol is widely distributed throughout the body and crosses the blood-brain barrier. Elimination is through hepatic metabolism, and inactive metabolites are excreted in the urine. Florfenicol is a good choice of antibiotics for treatment of intracellular pathogens.
Current Uses within OSU-VMC
- Treatment or control of bovine respiratory disease associated with Mannheimia spp., Pasteurella spp., and Histophilus spp. Some products include additional coverage for Mycoplasma bovis.
- Treatment of respiratory disease in small ruminants and camelids.
- Treatment of interdigital necrobacillosis (foot rot) or pododermatitis.
Contraindicated Uses
- Not approved for use in lactating dairy cattle (>20 months of age) or calves to be processed for veal.
Illegal Uses
- Although not illegal, since this product is not approved for use in lactating dairy cattle, a zero drug tolerance is established in any tissues (meat or milk) from dairy cattle > 20 months of age.
Formulations Available within the OSU Pharmacy
- Nuflor 300mg/ml injectable suspension
Notes
- In cattle, give injections only in the neck.
