Update 12/11/2020: The OSU Antimicrobial Stewardship Working Group (OSU-ASWG) is currently in the process of updating these guidelines to remain consistent with current veterinary literature and best practices. The updated guidelines are expected to be released in  2021.

Expected updates include:

  • Relevant references included on individual antimicrobial drug pages
  • Updated dosage/duration recommendations for ampicillin, ampicillin/sulbactam, amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and enrofloxacin
  • Updated drug classifications in the farm animal guidelines to further clarify appropriate label and off-label usage

If you have questions regarding our current AUG or would like additional information about the ongoing updates, please contact the OSU-ASWG at CVM-ASP@osu.edu.


The recommendations given in this guide are meant to serve as treatment guidelines, and are the opinions of the authors. We have attempted to verify that all information presented is correct, but ongoing antimicrobial research may invalidate these recommendations over time. When indicated, clinical judgement or consultation with the Antimicrobial Stewardship Working Group should be used to determine the best treatment choice and dosage for individual patients. If there is any doubt, please consult additional resources before making a treatment selection. Furthermore, these recommendations were developed for use at The Ohio State University Veterinary Medical Center and may not be appropriate for other settings.

Food Animal Disclaimer: Withdrawal times for meat and milk consumption must be established if not specifically stated on the label and the client must be informed that there is a withdrawal period.  The Food Animal Residue Avoidance Databank (www.farad.org) is a valuable resource to establish withdrawal times for drugs used in an extra label manner.


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OSU VMC Antimicrobial Use Guidelines Copyright © 2018 by The Ohio State University College of Veterinary Medicine is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.