Selected Antimicrobial Information – Farm Animal
Sulfadimethoxine [Farm Animal]
Restriction Status
Unrestricted
Dose
| Species | Usage | Dose |
|---|---|---|
| Camelids | For coccidiosis | 55mg/kg PO q24h |
| Cattle | Label Dose |
|
| Small Ruminants | Label Dose | No labeled dose. |
| Swine | Label Dose | No labeled dose. |
Brand Name(s)
Albon®, Agribon ®
Background
Sulfadimethoxine is a time-dependent, bacteriostatic sulfonamide antibiotic with activity primarily against Gram-positive and Gram-negative aerobes (though resistance is widespread among Enterobacteriaceae spp.), and to some lesser extent Gram-positive and Gram-negative anaerobes. It is also efficacious against Coccidia spp. Distribution throughout the body is wide, including across the blood-brain barrier and into respiratory secretions, and elimination is primarily in the urine as both active drug and metabolites.
Current Uses within OSU-VMC
- Treatment of bovine respiratory disease associated with Pasteurella spp., or calf diphtheria.
- Treatment of interdigital necrobacillosis (foot rot) or pododermatitis.
- Treatment of coccidiosis in camelids (only acceptable use in this species).
Contraindicated Uses
- Inactivated in the presence of purulent or necrotic material (e.g. abscesses).
Illegal Uses
- Not approved for use in female dairy cattle >20mos
Formulations Available within the OSU Pharmacy
- Albon 250 mg tablet
- Albon 50 mg/ml oral suspension
Notes
- Polioencephalomalacia (cerebrocortical necrosis) is a potential an adverse effect in ruminants and camelids.
