Selected Antimicrobial Information – Farm Animal

Sulfadimethoxine [Farm Animal]

Restriction Status



Species Usage Dose
Camelids For coccidiosis 55mg/kg PO q24h
Cattle Label Dose
  • 55mg/kg PO or IV once followed by 27.5mg/kg q24h PO or IV for up to 5d
  • Also available in boluses. See product label.
Small Ruminants Label Dose No labeled dose.
Swine Label Dose No labeled dose.

Brand Name(s)

Albon®, Agribon ®


Sulfadimethoxine is a time-dependent, bacteriostatic sulfonamide antibiotic with activity primarily against Gram-positive and Gram-negative aerobes (though resistance is widespread among Enterobacteriaceae spp.), and to some lesser extent Gram-positive and Gram-negative anaerobes. It is also efficacious against Coccidia spp. Distribution throughout the body is wide, including across the blood-brain barrier and into respiratory secretions, and elimination is primarily in the urine as both active drug and metabolites.

Current Uses within OSU-VMC

  • Treatment of bovine respiratory disease associated with Pasteurella spp., or calf diphtheria.
  • Treatment of interdigital necrobacillosis (foot rot) or pododermatitis.
  • Treatment of coccidiosis in camelids (only acceptable use in this species).

Contraindicated Uses

  • Inactivated in the presence of purulent or necrotic material (e.g. abscesses).

Illegal Uses

  • Not approved for use in female dairy cattle >20mos

Formulations Available within the OSU Pharmacy

  • Albon 250 mg tablet
  • Albon 50 mg/ml oral suspension


  • Polioencephalomalacia (cerebrocortical necrosis) is a potential an adverse effect in ruminants and camelids.


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OSU VMC Antimicrobial Use Guidelines Copyright © 2018 by The Ohio State University College of Veterinary Medicine is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.