Selected Antimicrobial Information – Farm Animal
Oxytetracycline [Farm Animal]
Restriction Status
Unrestricted
Dose
(Doses and indications may vary with brand name product. Consult product label.)
Species | Usage | Dose |
---|---|---|
Camelids | For susceptible pathogens |
|
Cattle | Oxytetracycline 200mg/mL (e.g. Liquamycin-200®, Bio-Mycin-200®) Label dose for pneumonia | 20mg/kg SQ, IV, or IM once |
Oxytetracycline 200mg/mL (e.g. Liquamycin-200®, Bio-Mycin-200®) Label dose for other indications | 6.6-11mg/kg SQ, IV, or IM q24h for up to 4d | |
Oxytetracycline 300mg/mL (e.g. Tetradure-300®) Label dose for pneumonia or pink eye | 20-30mg/kg IM or SQ once | |
Oxytetracycline 300mg/mL (e.g. Tetradure-300®) Label dose for other indications | 6.6-11mg/kg IM, SQ, or IV (given slowly) q24h for no more than 4d | |
Oxytetracycline 300mg/mL (e.g. Tetradure-300®) for combination products with flunixin (e.g. Hexasol®) | 30mg/kg IM or SQ once; do not give more than 10mL per injection site | |
Small Ruminants | For susceptible pathogens |
|
Swine | Tetradure-300® Label dose |
|
Brand Name(s)
Bio-Mycin® 200, Liquamycin (LA)-200®, Tetradure-300®, Hexasol, Terramycin® ointment, etc.
Background
Oxytetracycline is a time-dependent, bacteriostatic tetracycline antibiotic with a broad spectrum of activity against many Gram-positive and Gram-negative aerobes. It is not effective against Proteus spp. or Pseudomonas spp. Efficacy against clostridial organisms is variable. Intracellular organisms are highly susceptible. Distribution is widespread, but oxytetracycline does not enter the central nervous system. Oxytetracycline undergoes entero-hepatic recycling and is primarily excreted in the urine.
Current Uses within OSU-VMC
- Treatment of bovine or small ruminant respiratory disease associated with susceptible Pasteurella spp., Mannheimia spp., Histophilus spp., or Haemophilus spp., or calf diphtheria.
- Treatment of swine respiratory disease associated with susceptible Pasteurellaceae spp.
- Treatment of infectious bovine keratoconjunctivitis (pinkeye) associated with Moraxella bovis.
- Treatment of interdigital necrobacillosis (foot rot) or pododermatitis.
- Treatment enteritis (scours) in calves, small ruminants, and swine.
- Treatment of Wooden Tongue (Actinobacillus lignieresii).
- Treatment of leptospirosis in cattle and swine.
- Treatment of acute metritis or wound infections associated with Streptococcus or Staphylococcus spp.
- Treatment of in the face of an abortion outbreak in ewes associated with Chlamydophila spp., Campylobacter spp., or Coxiella burnetii.
Contraindicated Uses
- None
Illegal Uses
- None
Formulations Available within the OSU Pharmacy
- Oxytetra 100mg/ml injectable suspension
- Oxytetra 200 mg/ml injectable suspension
Notes
- None.